Xen BiofluiDx supplies four particle lines used to capture and detect a target, and one line of recombinant antigens used to calibrate the assay that measures it.
XEN Magnetic Beads are high-performance magnetic particles designed for biomolecular separation, molecular diagnostics, and automated laboratory workflows. Manufactured under strict quality control, they provide fast, reproducible, and scalable performance for research, OEM, and regulated diagnostic applications.
Key Features & Benefits
• Fast Magnetic Separation
Optimized magnetic properties enable at least 30% faster magnetic separation than standard market alternatives, increasing workflow efficiency and sample throughput.
• High Consistency & Reproducibility
A tightly controlled particle size distribution ensures excellent lot-to-lot consistency, delivering reliable performance for sensitive diagnostic and research assays.
• Advanced Surface Chemistry
Specially engineered surface coatings minimize nonspecific binding, resulting in cleaner assay signals, improved specificity, and greater analytical accuracy.
• Scalable & Reliable Manufacturing
Streamlined production processes ensure consistent product quality and dependable supply for both commercial manufacturing and diagnostic applications.
• Fluorophore-Free Design
XEN Magnetic Beads do not contain fluorescent dyes. They are designed specifically for target capture and magnetic separation, allowing compatibility with the detection chemistry already used in your assay.
Surface Chemistries
• Carboxyl (–COOH)
Supports stable covalent conjugation of antibodies, proteins, peptides, and nucleic acids using standard EDC/NHS coupling chemistry.
• Streptavidin
Provides high-affinity binding to biotin-labeled molecules for rapid, highly specific, and low-background capture applications.
Available Particle Sizes
XEN Magnetic Beads are available in one of the industry’s broadest size ranges, supporting applications from molecular targets to whole-cell separation.
• 100 nm
• 200 nm
• 300 nm
• 500 nm
• 1.5 µm
- Immunoassays and IVD
- Nucleic acid isolation (DNA and RNA)
- Protein purification and immunoprecipitation
- Cell separation and enrichment
- Automated sample preparation platforms
Xen Fluorescent Magnetic Beads uniquely combine magnetic separation and fluorescence detection in a single particle. Powered by quantum dot technology, they enable high-sensitivity, low-background, multiplexed detection workflows for next-generation diagnostics and research.
Because enrichment and readout happen on the same bead, a separate labelling step disappears from the workflow. The quantum dot core gives a narrow emission bandwidth for cleaner signals, high brightness for improved sensitivity, and a large separation between excitation and emission that reduces background noise. Fast magnetic response keeps wash and separation steps efficient, and every lot ships with certified fluorescence spectra and magnetic performance.
Five emission wavelengths are available, from 450 nm through to 665 nm. Xen is the only supplier offering built-in fluorescent magnetic beads across multiple emission wavelengths with customisation options.
- Multiplex immunoassays
- Fluorescence-based diagnostics and IVD
- High-throughput screening
- Advanced molecular diagnostics
- Research platforms using multi-colour detection
Xen Non-Quenched Fluorescent Beads are engineered for maximum assay sensitivity and stability. By integrating protective quantum dots into the core, these beads eliminate the photobleaching and excitation limits of standard dyes, giving a brighter and longer-lasting signal.
Unlike traditional fluorescent dyes that rapidly fade or quench under continuous light exposure, the inorganic quantum dot core guarantees zero photobleaching. Signal intensity stays reliable and ultra-stable during prolonged imaging, repeated measurements, and high-intensity laser excitation. Emission peaks are exceptionally sharp and well defined, which eliminates cross-channel optical bleed, and the very large separation between excitation and emission dramatically reduces autofluorescence and background noise.
All five colour wavelengths, from 450 nm to 665 nm, can be excited simultaneously from a single UV-to-blue light source in the 365 to 380 nm band. This removes the need for expensive, complex multi-laser setups in multiplexed assays. These beads are non-magnetic; if magnetic enrichment is also needed, see Fluorescent Magnetic Beads.
- High-sensitivity multiplex immunoassays requiring quantitative, multi-target detection from a single sample volume
- Flow cytometry calibration and standards, where stable optical properties make these an ideal reference
- Lateral flow and point-of-care diagnostics, where brightness and zero photobleaching give reliable quantification at low target concentrations
- Microfluidics and cellular imaging, enabling long-term tracking without signal degradation
Xen Time-Resolved Fluorescence particles are engineered for maximum sensitivity and superior signal clarity in immunoassays and diagnostic platforms. By using long-lifetime lanthanide fluorescence, they allow signal to be collected after background fluorescence has decayed, which dramatically improves the assay signal-to-noise ratio. Time-resolved fluorescence is widely regarded as one of the most sensitive fluorescence detection technologies for biomedical and diagnostic applications.
Two lanthanide channels are offered. Europium gives a sharp, well-defined red emission at 610 nm with a Stokes shift greater than 200 nm and a millisecond fluorescence lifetime, and is the gold standard for time-resolved immunoassays and diagnostic detection systems. Terbium gives a bright green emission at 545 nm with a long fluorescence lifetime and high resistance to photobleaching, providing a distinct second channel for multiplexing where spectral discrimination is critical.
The lanthanide chelates are encapsulated internally throughout the particle, so there is no dye leaching in aqueous systems, and high dye loading gives strong signal output with excellent storage stability. Particle size stays consistent before and after dye loading, with excellent monodispersity and stable dispersion that resists aggregation.
- Time-resolved immunoassays
- IVD and clinical diagnostics
- High-sensitivity biomarker detection
- Multiplex assay development
- OEM assay kit manufacturing
Controls and Calibrators is a set of recombinant antigens and one monoclonal antibody used to calibrate and standardise assays. Each item serves as a calibrator or standard in immunoassays and as an immunogen for antisera production.
Three cardiac items are available: the recombinant human cardiac Troponin I and C complex, recombinant human NT-proBNP, and NT-proBNP fused to a human IgG1 Fc domain, which produces a disulfide-linked homodimeric antigen format. Haematology is covered by recombinant human fetal haemoglobin, supplied as a tetramer of two beta and two gamma chains, and by monoclonal antibody 30D12, which recognises glycophorin A on human red blood cells and mediates erythrocyte agglutination. Infectious disease is covered by the SARS-CoV-2 nucleocapsid protein N-terminal domain.
Expression system matters when choosing. Material from HEK293 carries heterogeneous mammalian-type glycosylation, which gives a biologically relevant antigen but can affect recognition by antibodies raised against certain C-terminal epitopes. Material from E. coli carries no glycosylation. Purity is greater than 95% by SDS-PAGE for every item except fetal haemoglobin, which is greater than 90%.
- Calibrator or standard in immunoassays
- Immunogen for antisera production
- Assay standardisation and lot-to-lot control
All products are sold for research use only. Not for use in diagnostic procedures. Standard laboratory practices should be followed when handling these materials.